Exercise, the brain, and PD research

More evidence of the benefits of exercise on cognition in this New York Times article on exercise boosting levels of a substance (BDNF) thought to help in the regeneration of brain cells.

The article brings to mind the controversial trials of GDNF, an enzyme thought to help in the creation of new neurons, or brain cells. Amgen halted the trail because of safety concerns; some thought those fears were overblown. A complex case, for sure; an expert panel found no difference between placebo and GDNF, and noted that some in the trial developed anti-GDNF antibodies.

So maybe there still some hunt left in that neurotrophic growth factor dog, after all?